Gelatin-chlorin e6 conjugate for in vivo photodynamic therapy.
Jihwan SonGawon YiMoon-Hwa KwakSeung Mok YangJae Myung ParkBo-In LeeMyung-Gyu ChoiHeebeom KooPublished in: Journal of nanobiotechnology (2019)
This work demonstrates that a simple structure based on photosensitizer and gelatin can highly improve water solubility and stability. Superior tumor tissue accumulation and increased therapeutic efficacy of gelatin-Ce6 during in vivo PDT showed its high potential for clinical application.