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Gelatin-chlorin e6 conjugate for in vivo photodynamic therapy.

Jihwan SonGawon YiMoon-Hwa KwakSeung Mok YangJae Myung ParkBo-In LeeMyung-Gyu ChoiHeebeom Koo
Published in: Journal of nanobiotechnology (2019)
This work demonstrates that a simple structure based on photosensitizer and gelatin can highly improve water solubility and stability. Superior tumor tissue accumulation and increased therapeutic efficacy of gelatin-Ce6 during in vivo PDT showed its high potential for clinical application.
Keyphrases
  • photodynamic therapy
  • hyaluronic acid
  • bone regeneration
  • fluorescence imaging
  • tissue engineering
  • energy transfer