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The Effects of Immunosuppressive Drugs on the Characteristics and Functional Properties of Bone Marrow-Derived Stem Cells Isolated from Patients with Diabetes Mellitus and Peripheral Arterial Disease.

Jitka HusakovaBarbora EchalarJan KosslKaterina PalackaVladimira FejfarovaMichal Dubský
Published in: Biomedicines (2023)
The results indicate that IS drugs in a dose-dependent manner had a negative impact on the properties of BM-MSCs used to treat ischemic diabetic foot ulcers, and that these drugs could affect the therapeutic potential of BM-MSCs.
Keyphrases
  • stem cells
  • mesenchymal stem cells
  • umbilical cord
  • cell therapy
  • drug induced
  • oxidative stress
  • bone marrow
  • metabolic syndrome
  • skeletal muscle
  • glycemic control