Impact of comorbid Sjögren syndrome in anti-aquaporin-4 antibody-positive neuromyelitis optica spectrum disorders.
Tetsuya AkaishiToshiyuki TakahashiKazuo FujiharaTatsuro MisuJuichi FujimoriYoshiki TakaiShuhei NishiyamaMichiaki AbeTadashi IshiiMasashi AokiIchiro NakashimaPublished in: Journal of neurology (2021)
The prevalence of SjS is higher among AQP4-IgG-positive than AQP4-IgG-negative patients, with the potential prevalence of 10-20% at the diagnosis of AQP4-IgG-positive NMOSD. Comorbid SjS is more prevalent in females, and it has a higher relapse frequency among AQP4-IgG-positive patients.