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Self-Powered Point-of-Care Device for Galvanic Cell-Based Sample Concentration Measurement.

Albert Álvarez-CarullaYaiza Montes-CebriánJordi Colomer-FarraronsPere Lluís Miribel-Català
Published in: Sensors (Basel, Switzerland) (2021)
A novel self-powered point-of-care low-power electronics approach for galvanic cell-based sample concentration measurement is presented. The electronic system harvests and senses at the same time from the single cell. The system implements a solution that is suitable in those scenarios where extreme low power is generated from the fuel cell. The proposed approach implements a capacitive-based method to perform a non-linear sweep voltammetry to the cell, but without the need to implement a potentiostat amplifier for that purpose. It provides a digital-user readable result without the need for external non-self-powered devices or instruments compared with other solutions. The system conception was validated for a particular case. The scenario consisted of the measurement of a NaCl solution as the electrolyte, which was related to the conductivity of the sample. The electronic reader continuously measured the current with a transfer function gain of 1.012 V mA-1. The overall system exhibited a maximum coefficient of variation of 6.1%, which was an improvement compared with the state-of-the-art. The proof of concept of this electronics system was validated with a maximum power consumption of 5.8 μW using commercial-off-the-self parts.
Keyphrases
  • single cell
  • rna seq
  • cell therapy
  • climate change
  • high throughput
  • magnetic resonance imaging
  • computed tomography
  • mesenchymal stem cells
  • magnetic resonance
  • bone marrow
  • patient reported outcomes