Thalamic energy dysfunction is associated with thalamo-cortical tract damage in multiple sclerosis: A diffusion spectroscopy study.

Vito A G RiciglianoMatteo ToniettoRaffaele PalladinoEmilie PoirionAlberto De LucaFrancesca BranzoliGeraldine BeraElisabeth MaillartBruno StankoffBenedetta Bodini

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2020)

Reduced thalamic ADC(tCr) correlates with thalamo-cortical tract damage in MS, showing that pathologic changes in thalamic energy metabolism are associated with structural degeneration of connected fibers.

Keyphrases

multiple sclerosis
deep brain stimulation
oxidative stress

mass spectrometry
high resolution
regulatory t cells

single molecule
magnetic resonance

computed tomography
immune response