Predictive value of ultrasound doppler parameters in neoadjuvant chemotherapy response of breast cancer: Prospective comparison with magnetic resonance and mammography.
Livia ConzRodrigo Menezes JalesMaira Teixeira DóriaIsabelle MelloniCarla Andries Cres LyrioCarlos MenossiSophie DerchainLuís Otavio SarianPublished in: PloS one (2024)
This study provides evidence that mid-treatment Doppler US and other imaging modalities can be used to predict the response to NACT in breast cancer patients. Functional parameters, such as blood flow velocities and SWE measurements, demonstrated superior predictive value for pCR, while morphological parameters had limited value. These findings have implications for personalized treatment strategies and may contribute to improved outcomes in the management of breast cancer.
Keyphrases
- blood flow
- neoadjuvant chemotherapy
- magnetic resonance
- locally advanced
- contrast enhanced
- lymph node
- magnetic resonance imaging
- high resolution
- sentinel lymph node
- squamous cell carcinoma
- type diabetes
- metabolic syndrome
- computed tomography
- adipose tissue
- early stage
- mass spectrometry
- insulin resistance
- ultrasound guided
- fluorescence imaging
- contrast enhanced ultrasound
- clinical evaluation