Are tyrosine kinase inhibitors an effective treatment in testicular metastases from kidney cancer? Case report.
Ursula Maria VoglMarcello TucciRosario Francesco Di StefanoAlessandro SamuellyMaristella BungaroEnrico BollitoGiorgio Vittorio ScagliottiConsuelo ButtiglieroPublished in: Tumori (2021)
Testicular metastases from renal cell carcinoma (RCC) are extremely rare. Tyrosine kinase inhibitors (TKI) are the cornerstone of systemic therapy for metastatic RCC. We report a case of testicular metastasis in a 72-year-old patient with RCC that developed 17 years after nephrectomy and response to TKI treatment, a retrospective literature search on testicular metastases from RCC, and the indirect evidence described in the literature on the efficacy of chemotherapy and target therapy on testicular lesions.