MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma That Is Reversible through Restoration of Proinflammatory Macrophages.

Renumathy Dhanasekaran Aida S Hansen Jangho Park Lea Lemaitre Ian Lai Nia Adeniji Sibu P Kuruvilla Akanksha Suresh Josephine Zhang Varsha Swamy Dean W Felsher

Published in: Cancer research (2023)

Macrophage-mediated immune evasion is a therapeutic vulnerability of MYC-driven cancers, which has implications for prioritizing MYC-driven hepatocellular carcinoma for combination immunotherapy.

Keyphrases

transcription factor
climate change
cell proliferation
adipose tissue