Login / Signup

Reversible dysregulation of renal circadian rhythm in lupus nephritis.

Rakesh MishraRamalingam BethunaickanCeline C BerthierZhengzi YiJoshua J StrohlPatricio T HuertaWeijia ZhangAnne Davidson
Published in: Molecular medicine (Cambridge, Mass.) (2021)
Our studies indicate the role of inflammation in causing the circadian disruption and suggest that screening for loss of normal blood pressure dipping should be incorporated into LN management. The data also suggest a potential role for circadian agonists in the treatment of lupus nephritis.
Keyphrases
  • blood pressure
  • heart rate
  • oxidative stress
  • electronic health record
  • big data
  • machine learning
  • skeletal muscle
  • case control
  • adipose tissue
  • replacement therapy