The PRKAR1B p.R115K Variant is Associated with Lipoprotein Profile in African American Youth with Metabolic Challenges.

Michelle BloydNikolaos SettasFabio Rueda FauczNinet SinaiiKerstin BathonJames IbenSteven CoonSonia CaprioConstantine A StratakisEdra London

Published in: Journal of the Endocrine Society (2021)

Data suggest PRKAR1B p.R115K affects cAMP signaling and may favorably modulate lipoprotein profile in African American youth, protecting them from some adverse metabolic outcomes.

Keyphrases

african american
mental health
physical activity
young adults
low density lipoprotein
electronic health record
big data
type diabetes
adipose tissue
protein kinase