TIM-3 Dictates Functional Orientation of the Immune Infiltrate in Ovarian Cancer.
Jitka FucikovaJana RakovaMichal HenslerLenka KasikovaLucie BelicovaKamila HladikovaIva TruxovaPetr SkapaJan LacoLadislav PecenIvan PraznovecMichael Jiří HalaškaTomas BrtnickyRoman KodetAnna FialovaJosephine PineauAlain GeyEric TartourAleš RyškaLorenzo GalluzziRadek SpisekPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
Our data indicate that PD-L1 and TIM-3 constitute prognostically relevant biomarkers of active and suppressed immune responses against HGSC, respectively.