The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization.

Maryam AlqabandiNicola de FranceschiSourav MaityNolwenn MiguetMarta BallyWouter H RoosWinfried WeissenhornPatricia BassereauStéphanie Mangenot

Published in: BMC biology (2021)

We therefore conclude that CHMP2B and CHMP2A exhibit different mechanical properties and might thus contribute differently to the diverse ESCRT-III-catalyzed membrane remodeling processes.

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