Circulating Dipeptidyl Peptidase 3 Modulates Systemic and Renal Hemodynamics Through Cleavage of Angiotensin Peptides.
Adrien PicodSandrine PlacierMagali GenestJacques CallebertNathan JulianMaxime ZalcNoma AssadHugo NordinKarine SantosStéphane GaudryChristos ChatziantoniouAlexandre MebazaaFeriel AzibaniPublished in: Hypertension (Dallas, Tex. : 1979) (2024)
High circulating DPP3 increases renal blood flow due to reduced AT1R activation via decreased concentrations of circulating angiotensin peptides while blood pressure is maintained by concomitant endogenous catecholamines release.