Genetic variant rs1205 is associated with COVID-19 outcomes: The Strong Heart Study and Strong Heart Family Study.

Lyle G Best Esther ErdeiKarin HaackJack W KentKimberly M MalloyDeborah E NewmanMarcia O'LearyRae A O'LearyQuan SunAna Navas-AcienNora FranceschiniShelley A Cole

Published in: PloS one (2024)

A T-dominant genotype of rs1205 in the CRP gene is associated with COVID-19 death or hospitalization, even after adjustment for relevant clinical factors and potential participant relatedness. Additional study of other populations and genetic variants of this gene are warranted.

Keyphrases

sars cov
coronavirus disease
genome wide
dna methylation
risk assessment
metabolic syndrome
transcription factor
climate change
respiratory syndrome coronavirus