Genetic Predisposition to Adverse Neurodevelopmental Outcome of Extremely Low Birth Weight Infants.

Michael W VarnerElizabeth A ThomC Michael CottenSusan R HintzGrier P PageDwight J RouseBrian M MercerMaged M CostantineYoram SorokinJohn M ThorpSusan M RaminMarshall W CarpenterMary J O'SullivanAlan M PeacemanGeorge R SaadeDonald J DudleySteve N Caritisnull null

Published in: American journal of perinatology (2023)

· Early preterm and ELBW infants have dramatically increased risks of CP and developmental delay.. · A genetic variant in SERPINE1 is associated with CP or death among ELBW infants.. · The SERPINE1 gene encodes the serine protease inhibitor plasminogen activator inhibitor..

Keyphrases

low birth weight
preterm infants
preterm birth
human milk
genome wide
copy number
emergency department
climate change
adverse drug
genome wide analysis
drug induced