Large-scale genome sequencing redefines the genetic footprints of high-altitude adaptation in Tibetans.

Wangshan ZhengYaoxi HeYongbo GuoTian YueHui ZhangJun LiBin ZhouXuerui ZengLiya LiBin WangJingxin CaoLi ChenChunxia LiHongyan LiChaoying CuiCaijuan Bainull BaimakangzhuoXuebin Qinull OuzhuluobuBing Su

Published in: Genome biology (2023)

Overall, the large-scale Tibetan WGS data and the identified adaptive variants/genes can serve as a valuable resource for future genetic and medical studies of high-altitude populations.

Keyphrases

genome wide
copy number
dna methylation
healthcare
electronic health record
current status
single cell
big data
gene expression
transcription factor
machine learning
genome wide identification
genetic diversity
bioinformatics analysis