Tumor Targeting via Sialic Acid: [68Ga]DOTA-en-pba as a New Tool for Molecular Imaging of Cancer with PET.

Charalambos TsoukalasSimonetta Geninatti-CrichAnastasios GaitanisTheodoros TsotakosMaria Paravatou-PetsotasSilvio AimeRogelio Jiménez-JuárezConstantinos D AnagnostopoulosKristina DjanashviliPenelope Bouziotis

Published in: Molecular imaging and biology (2019)

Our work is the first attempt for in vivo imaging of cancer by targeting overexpression of sialic acid on cancer cells with a radiotracer in PET.

Keyphrases

pet ct
papillary thyroid
pet imaging
squamous cell
computed tomography
positron emission tomography
high resolution
cell proliferation
lymph node metastasis
squamous cell carcinoma
childhood cancer
transcription factor
drug delivery
photodynamic therapy