Mechanical force modulates periodontal ligament stem cell characteristics during bone remodelling via TRPV4.

Shan-Shan JinDan-Qing HeYu WangTing ZhangHua-Jie YuZi-Xin LiLi-Sha ZhuYan-Heng ZhouYan Liu

Published in: Cell proliferation (2020)

Taken together, we show here that TRPV4 activation in PDLSCs under mechanical force contributes to changing their stem cell characteristics and modulates bone remodelling during tooth movement.

Keyphrases

stem cells
bone mineral density
single molecule
neuropathic pain
soft tissue
bone loss
bone regeneration
postmenopausal women
cell therapy
spinal cord injury
body composition