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Gene inactivation of lysyl oxidase in smooth muscle cells reduces atherosclerosis burden and plaque calcification in hyperlipidemic mice.

Filipe F Stoyell-ContiMaya Suresh KumarZachary M ZigmondMiguel G RojasNieves Santos FalconLaisel MartinezRoberto I Vazquez-Padron
Published in: Atherosclerosis (2024)
Lox inactivation in SMC protects mice against atherosclerosis and plaque calcification by reducing SMC modulation and FAK/β-catenin signaling.
Keyphrases
  • high fat diet induced
  • cardiovascular disease
  • coronary artery disease
  • chronic kidney disease
  • genome wide
  • copy number
  • type diabetes
  • risk factors
  • insulin resistance
  • cell migration
  • genome wide identification