Rotational thromboelastometry can predict the probability of bleeding events in a translational rat model of haemophilia A following gene-based FVIIa prophylaxis.

Malte Selch LarsenRasmus Vestergaard JuulShannon M ZintnerAnnemarie T KristensenParis MargaritisMads Kjelgaard-HansenBo WiinbergUlrika S H SimonssonMads Kreilgaard

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2019)

Using PK-CT-RTTE modelling, we demonstrated that ROTEM parameters can accurately predict the probability of bleeding events in a translational animal model of haemophilia A.

Keyphrases

atrial fibrillation
image quality
copy number
contrast enhanced
genome wide
dual energy
magnetic resonance imaging
positron emission tomography
transcription factor