Comparison between placental and skeletal muscle ECM: in vivo implantation.

Carla Maria F CarvalhoLuciano C P C LeonelRafael R CañadaRodrigo S N BarretoDurvanei A MariaMariano Del SolMaria Angélica MiglinoSonja E Lobo

Published in: Connective tissue research (2020)

These results demonstrated that xenogeneic placental ECM, implanted heterotopically (representing a biologically critical and challenging microenvironment), induced local inflammatory reactions similar to the allogeneic muscle ECM, implanted orthotopically. Thus, placenta-derived extracellular matrix must be further explored in regenerative medicine.

Keyphrases

extracellular matrix
skeletal muscle
stem cell transplantation
insulin resistance
high glucose
diabetic rats
stem cells
bone marrow
oxidative stress
drug induced
low dose
type diabetes
high dose