Chemiluminescent organic nanophotosensitizer for a penetration depth independent photodynamic therapy.
Xiaomei LuXingwen SongQi WangWenbo HuWei ShiYufu TangZizi WuQu-Li FanWei HuangPublished in: RSC advances (2020)
Photodynamic therapy initiated by external photoexcitation is a clinically-approved therapeutic paradigm, but its practical application has been severely hindered by the shallow penetration of light. Here, we describe a penetration-independent PDT modality using a chemiluminescent organic nanophotosensitizer, which is activated by hydrogen peroxide instead of external photoexcitation.