Electrochemically promoted oxidative α-cyanation of tertiary and secondary amines using cheap AIBN.

Qing-Wen GuiZhi-Yuan XiongFan TengTian-Cheng CaiQiang LiWenxia HuXiaoli WangJialing YuXiaoying Liu

Published in: Organic & biomolecular chemistry (2021)

The electrochemical α-cyanation of tertiary and secondary amines has been developed by using a cheap cyanide reagent, azobisisobutyronitrile (AIBN). The CN radical, generated through n-Bu4NBr-meidated electrochemical oxidation, participates in a novel α-cyanation reaction under exogenous oxidant-free conditions.

Keyphrases

gold nanoparticles
electron transfer
molecularly imprinted
ionic liquid
label free
lymph node metastasis
hydrogen peroxide
squamous cell carcinoma
high resolution
solid phase extraction