Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction.
Bonpei TakaseYukie KobayashiNatsuko SasakiKatsumi HayashiTetsuya HisadaMasami SakuradaNobuyuki MasakiMasayoshi NagataPublished in: Oxford medical case reports (2022)
ST-segment elevation myocardial infarction (STEMI) can be caused by coronary artery vasospasm (VSA) due to endothelial dysfunction. However, the clinical role of endothelial function tests in VSA-induced STEMI is not fully understood. We present the case of a 43-year-old woman with atypical chest pain and no coronary risk factors. STEMI caused by VSA was diagnosed. Flow-mediated vasodilatation (FMD) and EndPAT tests were performed; the FMD and reactive hyperaemia index were 3.8% and 1.23, respectively. Endothelial dysfunction is the putative cause of STEMI. FMD and EndPAT tests might be useful for predicting adverse outcomes in young premenopausal women with VSA.
Keyphrases
- st segment elevation myocardial infarction
- percutaneous coronary intervention
- coronary artery
- coronary artery disease
- st elevation myocardial infarction
- risk factors
- high glucose
- subarachnoid hemorrhage
- acute coronary syndrome
- diabetic rats
- postmenopausal women
- pulmonary artery
- drug induced
- endothelial cells
- heart failure
- left ventricular
- pulmonary hypertension
- middle aged
- cerebral ischemia
- blood brain barrier
- ejection fraction