Comparative Clinical Outcomes With Scale-up of Dolutegravir as First-Line Antiretroviral Therapy in Ukraine.
Konstantin DumchevTetiana KiriazovaSerhiy RiabokonAlyona ShostCanada ParrishAnna ShapovalMyroslava GermanovychJeremy PennerJason BesteNancy PuttkammerPublished in: Journal of acquired immune deficiency syndromes (1999) (2022)
DTG-based regimens were comparable with LPV and more effective than EFV in achieving viral suppression among ART-naive patients in a multisite cohort in Ukraine. Treatment retention was equally high in all 3 groups. This evidence from Ukraine supports the ART Optimization Initiative as a strategy to improve efficiency of the ART program without negatively affecting patient clinical outcomes.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv infected patients
- human immunodeficiency virus
- hiv positive
- hiv aids
- end stage renal disease
- quality improvement
- ejection fraction
- newly diagnosed
- sars cov
- peritoneal dialysis
- prognostic factors
- patient reported outcomes
- patient reported
- replacement therapy
- smoking cessation
- combination therapy
- men who have sex with men