An ionic liquid-molecularly imprinted composite based on graphene oxide for the specific recognition and extraction of cancer antigen 153.
Shuang HanAixin YaoYuan WangPublished in: RSC advances (2021)
Molecularly imprinted polymers with graphene oxide (GO) as a carrier (GMIPs) were synthesized to selectively recognize and capture cancer antigen 153 (CA153). The results show that the MIP has good selectivity and adsorption for CA153, and has strong anti-interference ability. Molecularly imprinted solid phase extraction (MISPE) combined with ultra performance liquid chromatography (UPLC) for the specific adsorption of CA153 was also established, and showed great potential for the analysis of CA153 in clinics in the future.
Keyphrases
- molecularly imprinted
- solid phase extraction
- liquid chromatography
- ionic liquid
- simultaneous determination
- high performance liquid chromatography
- papillary thyroid
- liquid chromatography tandem mass spectrometry
- tandem mass spectrometry
- mass spectrometry
- gas chromatography mass spectrometry
- protein kinase
- high resolution mass spectrometry
- ultra high performance liquid chromatography
- squamous cell
- primary care
- gas chromatography
- room temperature
- lymph node metastasis
- current status
- high resolution
- ms ms
- young adults
- childhood cancer