Mechanisms of Xiaozheng decoction for anti-bladder cancer effects via affecting the GSK3β/β-catenin signaling pathways: a network pharmacology-directed experimental investigation.

Jingming ZhuangJiahang MoZhengnan HuangYilin YanZeyi WangXiangqian CaoChenkai YangBing ShenFang Zhang

Published in: Chinese medicine (2023)

By employing network pharmacology and conducting in vitro experiments, the mechanism of Xiaozheng decoction's effect against bladder cancer was tentatively elucidated, and its main active ingredients and targets were identified, providing a scientific basis for future research.

Keyphrases

signaling pathway
pi k akt
epithelial mesenchymal transition
cell proliferation
current status
muscle invasive bladder cancer
network analysis
oxidative stress