Reduction in Intrahepatic cccDNA and Integration of HBV in Chronic Hepatitis B Patients with a Functional Cure.
Weiqiang GanNa GaoLin GuZhishuo MoXiuqing PangZiying LeiZhi-Liang GaoPublished in: Journal of clinical and translational hepatology (2022)
After achieving an FC, the rate of intrahepatic cccDNA and HBV integration was significantly reduced in patients with CHB. For those patients who cleared intrahepatic cccDNA, the chances of developing virological relapse were even lower.