Longitudinal Study of Analgesic Use and Risk of Incident Persistent Tinnitus.
Sharon G CurhanJordan GlicksmanMolin WangRoland D EaveyGary C CurhanPublished in: Journal of general internal medicine (2022)
The risk of developing persistent tinnitus was not elevated among frequent low-dose aspirin users. Among younger women, frequent moderate-dose aspirin use was associated with higher risk. Frequent NSAID use and frequent acetaminophen use were associated with higher risk of incident persistent tinnitus among all women, and the magnitude of the risks tended to be greater with increasing frequency of use. Our results suggest analgesic users are at higher risk for developing tinnitus and may provide insight into the precipitants of this challenging disorder, but additional investigation to determine whether there is a causal association is needed.
Keyphrases
- low dose
- hearing loss
- polycystic ovary syndrome
- cardiovascular disease
- cardiovascular events
- high dose
- breast cancer risk
- pregnancy outcomes
- neuropathic pain
- antiplatelet therapy
- anti inflammatory
- coronary artery disease
- pregnant women
- risk assessment
- insulin resistance
- human health
- spinal cord injury
- liver injury
- anti inflammatory drugs