Using Human Plasma as an Assay Medium in Caco-2 Studies Improves Mass Balance for Lipophilic Compounds.

Kasiram KatneniThao PhamJessica SaundersGong ChenRahul PatilKaren L WhiteNada AblaFrancis C K ChiuDavid M ShacklefordSusan A Charman

Published in: Pharmaceutical research (2018)

The results support the utility of human plasma as an alternate Caco-2 assay medium to improve mass balance and permeability measurements for lipophilic compounds.

Keyphrases

high throughput
single cell