Maternal obesity reduces placental autophagy marker expression in uncomplicated pregnancies.

Matthew CohenEmily GuoAidan PucchioBarbra de VrijerTrevor G ShepherdGenevieve D Eastabrook

Published in: The journal of obstetrics and gynaecology research (2020)

Obesity leads to reduced placental autophagy in uncomplicated pregnancies; thus, changes in autophagy may be involved in the underlying mechanisms of obesity-related placental diseases of pregnancy.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
cell death
pregnancy outcomes
endoplasmic reticulum stress
high fat diet induced
preterm birth
type diabetes
weight gain
signaling pathway
oxidative stress
birth weight
gestational age
urinary tract infection
adipose tissue
body mass index
drug induced