Phenotype-Genotype Correlations and Distribution of Key Virulence Factors in Enterococcus faecalis Isolated from Patients with Urinary Tract Infections.
Yomna A HashemKhaled A AbdelrahmanRamy Karam AzizPublished in: Infection and drug resistance (2021)
A clear variability in virulence gene distribution among the isolates was observed, and no particular pattern was associated with UTI. Whereas all isolates carried at least ace and pil, whose products are involved in adherence, which is a virulence phenotype that is required for urinary colonization, six isolates carried the entire set of investigated genes. Statistical analysis of the results suggests cyl as a biomarker for hemolytic activity, fsrB as a diagnostic biomarker for the gelatinase activity, and gelE-sprE as predictors for biofilm formation strength in E. faecalis.
Keyphrases
- biofilm formation
- urinary tract infection
- pseudomonas aeruginosa
- staphylococcus aureus
- escherichia coli
- candida albicans
- genetic diversity
- genome wide
- cystic fibrosis
- genome wide identification
- antimicrobial resistance
- copy number
- genome wide analysis
- type diabetes
- angiotensin ii
- high resolution
- metabolic syndrome
- adipose tissue
- bioinformatics analysis