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Stage-dependent angiopoietin-Tie2 and nitric oxide signaling of erythrocytes in response to surgical trauma in head and neck cancer.

Hsiang-Ling WuYou-Hsiang ChuYing-Hsuan TaiMei-Yung TsouCheng-Hsien WuWen-Liang LoShyh-Kuan TaiChun-Chang YehChih-Cherng Lu
Published in: World journal of surgical oncology (2020)
The dynamic change of angiopoietin-Tie2 signaling in the erythrocyte membrane along with the enhanced nitric oxide in plasma after tumor resection suggests erythrocytes play a significant role in modulating surgery-induced angiogenesis, which may provide a novel marker for cancer surveillance and control.
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