Waist-hip ratio related genetic loci are associated with risk of impaired fasting glucose in Chinese children: a case control study.
Qi-Ying SongXiang-Rui MengAnke HinneyJie-Yun SongTao HuangJun MaHai-Jun WangPublished in: Nutrition & metabolism (2018)
We identified individual effects of rs6795735 (ADAMTS9), rs984222 (TBX15-WARS2), and rs1011731 (DNM3-PIGC) on glycemic phenotypes in Chinese children for the first time. The study suggests that genetic predisposition to central obesity is associated with impaired fasting glucose, providing more evidence for the pathogenesis of diabetes.
Keyphrases
- blood glucose
- type diabetes
- insulin resistance
- glycemic control
- genome wide
- young adults
- metabolic syndrome
- cardiovascular disease
- body mass index
- weight loss
- copy number
- adipose tissue
- weight gain
- dna methylation
- skeletal muscle
- total hip arthroplasty
- body weight
- genome wide association study
- genome wide association