Trends in adverse drug reactions related to oral weak opioid analgesics in therapeutic use in adults: A 10-year French vigilances retrospective study.

Weniko CareSylvine PinelLaurène DufayetJérôme LangrandJoëlle MicallefDominique Vodovar

Published in: Fundamental & clinical pharmacology (2023)

ADRs mostly occurred among young women using tramadol, without significant variation in the number of reported cases over time. Serious ADRs were more frequently reported to the Pharmacovigilance database, particularly for codeine. Women seemed to be at greater risk of ADRs.

Keyphrases

adverse drug
electronic health record
drug induced
emergency department
polycystic ovary syndrome
chronic pain
postoperative pain
pregnant women
cervical cancer screening