In hospitalized patients undergoing therapeutic plasma exchange, major bleeding prevalence depends on the bleeding definition: An analysis of The Recipient Epidemiology and Donor Evaluation Study-III.
Alexandre Soares Ferreira JuniorMorgana Pinheiro Maux LessaKate SanbornMaragatha KuchibhatlaMatthew S KarafinOluwatoyosi Adefunke OnwuemenePublished in: Journal of clinical apheresis (2023)
Among hospitalized adults undergoing TPE in the REDS-III study, the prevalence of major bleeding was 17.3%. The addition of PRBC and Hgb decline to ICD codes increased bleeding prevalence threefold. Future studies are needed to develop validated models that identify patients at risk for major bleeding during TPE.