A comparative study of INSM1 (clone MRQ70) immunoreactivity on CytoLyt® pretreated cytology and resection specimens of pancreatic neuroendocrine tumors.

Published in: Diagnostic cytopathology (2024)

The choice of fixative has a demonstrable effect on the immunoreactivity of INSM1 in PanNET. Even though the sensitivity is lower in CytoLyt®-fixed cell block specimens, the addition of INSM1 is useful, especially in challenging cases that may be negative for one or more of the traditional NE markers.

Keyphrases

neuroendocrine tumors
fine needle aspiration
ultrasound guided
single cell
cell therapy
bone marrow
mesenchymal stem cells