Rheumatoid arthritis, quantitative parenchymal lung features, and mortality among smokers.
Gregory C McDermottKeigo HayashiKazuki YoshidaPierre-Antoine JugeMatthew MollMichael H ChoTracy J DoyleGregory L KinneyPaul F DellaripaZachary S WallaceElizabeth A ReganGary M HunninghakeEdwin K SilvermanSamuel Y AshRaul San Jose EsteparGeorge R WashkoJeffrey A SparksPublished in: Rheumatology (Oxford, England) (2023)
Using machine learning-derived QCT data in a cohort of smokers, RA was associated with higher percentage of interstitial changes. The combination of RA and emphysema conferred >5-fold higher mortality.
Keyphrases
- rheumatoid arthritis
- disease activity
- smoking cessation
- cardiovascular events
- ankylosing spondylitis
- interstitial lung disease
- risk factors
- chronic obstructive pulmonary disease
- electronic health record
- systemic lupus erythematosus
- high resolution
- lung function
- idiopathic pulmonary fibrosis
- type diabetes
- machine learning
- cardiovascular disease
- mass spectrometry
- artificial intelligence