Polymeric Propranolol Nanoparticles for Intraocular Delivery: Formulation, Characterization, and Vitreous Pharmacokinetics.

Farkhondeh ChaharbandReyhaneh VarshochianRassoul DinarvandHamideh SabbaghiMozhgan Rezaei KanaviNarsis DaftarianMazda Rad-Malekshahi

Published in: Journal of ophthalmic & vision research (2024)

PLGA NPs can prolong the existence of propranolol in both vitreous and posterior ocular tissues, and thus, may provide an effective approach in treatment of posterior segment neovascularization.

Keyphrases

drug delivery
drug release
gene expression
cancer therapy
vascular endothelial growth factor
cataract surgery
bone regeneration