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Quinazoline-2,4(1 H,3 H)-dione Scaffold for development of a novel PARP-targeting PET probe for tumor imaging.

Chunfeng HeHui ShiBoyu TanZhaoning JiangRui CaoJiamin ZhuKun QianXiao WangXiaoping XuChunrong QuShaoli SongZhen Cheng
Published in: European journal of nuclear medicine and molecular imaging (2024)
Ga]Ga-SMIC-2001 is a highly promising PET probe capable of imaging tumors with PARP overexpression.
Keyphrases
  • pet ct
  • high resolution
  • dna damage
  • positron emission tomography
  • dna repair
  • computed tomography
  • quantum dots
  • living cells
  • cell proliferation
  • cancer therapy
  • fluorescence imaging
  • photodynamic therapy