Analysis of serum inflammatory mediators in type 2 diabetic patients and their influence on renal function.

Liliane Silvano AraújoMarcos Vinícius da SilvaCrislaine Aparecida da SilvaMaria de Fátima BorgesHeloísa Marcelina da Cunha PalharesLaura Penna RochaRosana Rosa Miranda CorrêaVirmondes Rodrigues JúniorMarlene Antônia Dos ReisJuliana Reis Machado

Published in: PloS one (2020)

Increased levels of TNFR1, adipokines, chemokines and decrease of IL-4 play important role in the inflammatory process developed in T2DM and decreased renal function. We also suggest that TNFR1 is a strong predictor of renal dysfunction in patients with T2DM.

Keyphrases

end stage renal disease
oxidative stress
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
metabolic syndrome
adipose tissue
glycemic control
skeletal muscle
patient reported