An integrated molecular risk score early in life for subsequent childhood asthma risk.

Andreas BöckKathrin UrnerJana Kristin Eckert Michael Salvermoser Kristina Laubhahn Sonja KunzeJörg KumbrinkMarc P HoeppnerKathrin KalkbrennerSimone Kreimeier Kirsten Beyer Hamelmann Eckard Michael KabeschMartin DepnerGesine HansenJosef RiedlerMarjut Roponen Elisabeth Schmausser-Hechfellner Cindy Barnig Amandine Divaret-Chauveau Anne M Karvonen Juha PekkanenRemo FreiCaroline Roduit Roger Lauener Bianca Schaubnull null

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2024)

Applying epidemiological predictors alone showed moderate predictive abilities. Molecular markers from birth modestly improved prediction. Allergic symptoms/diagnoses enhanced the power of prediction, which is important for clinical practice and for the design of future studies with molecular markers.

Keyphrases

clinical practice
single molecule
high intensity
lung function
pregnant women
allergic rhinitis
physical activity
sleep quality
breast cancer risk