QbD-Based Investigation of Dermal Semisolid in situ Film-Forming Systems for Local Anaesthesia.
Anita KovácsNikolett KisMária Budai-SzűcsAttila GácsiErzsébet CsányiIldikó CsókaSzilvia BerkóPublished in: Drug design, development and therapy (2020)
Our results show that LID-HCl has great influence on the critical parameters of FFSs. The silicone content can improve the applicability of formulations and has a favorable effect on the permeation rate of LID-HCl into the skin.