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The presence of genetic risk variants within PTPN2 and PTPN22 is associated with intestinal microbiota alterations in Swiss IBD cohort patients.

Bahtiyar YilmazMarianne R SpalingerLuc BiedermannYannick FrancNicolas FournierJean-Benoit RosselPascal JuilleratGerhard RoglerAndrew J MacphersonMichael Scharl
Published in: PloS one (2018)
We identified that IBD-associated genetic risk variants, disease severity and the interaction of these factors are related to significant alterations in intestinal microbiota composition of IBD patients.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • chronic kidney disease
  • newly diagnosed
  • copy number
  • peritoneal dialysis
  • genome wide
  • gene expression
  • patient reported outcomes
  • ulcerative colitis