The presence of genetic risk variants within PTPN2 and PTPN22 is associated with intestinal microbiota alterations in Swiss IBD cohort patients.
Bahtiyar YilmazMarianne R SpalingerLuc BiedermannYannick FrancNicolas FournierJean-Benoit RosselPascal JuilleratGerhard RoglerAndrew J MacphersonMichael ScharlPublished in: PloS one (2018)
We identified that IBD-associated genetic risk variants, disease severity and the interaction of these factors are related to significant alterations in intestinal microbiota composition of IBD patients.