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Liver Damage and Impaired Coagulation in COVID-19 Patients: A Case Series.

Ludovico Montebianco AbenavoliIsabella AquilaMatteo Antonio SaccoGiuseppe Guido Maria ScarlataAnna Caterina ProcopioLuigi BoccutoEmidio ScarpelliniMarta GrecoDaniela Patrizia FotiPietrantonio RicciFrancesco Luzza
Published in: Diseases (Basel, Switzerland) (2023)
Our results indicate that in subjects with a severe form of COVID-19, liver disease is related to changes in coagulative and fibrinolytic pathways. In particular, we noted low fibrinogen levels and high D-dimer levels with histological liver findings. Our data suggest that fibrinogen and D-dimers may be used as prognostic markers to detect the severity of liver disease in patients with COVID-19. Finally, we underline the crucial role of coagulation balance in subjects with severe forms of COVID-19.
Keyphrases
  • sars cov
  • coronavirus disease
  • early onset
  • respiratory syndrome coronavirus
  • oxidative stress
  • electronic health record
  • big data
  • data analysis