Liver Damage and Impaired Coagulation in COVID-19 Patients: A Case Series.
Ludovico Montebianco AbenavoliIsabella AquilaMatteo Antonio SaccoGiuseppe Guido Maria ScarlataAnna Caterina ProcopioLuigi BoccutoEmidio ScarpelliniMarta GrecoDaniela Patrizia FotiPietrantonio RicciFrancesco LuzzaPublished in: Diseases (Basel, Switzerland) (2023)
Our results indicate that in subjects with a severe form of COVID-19, liver disease is related to changes in coagulative and fibrinolytic pathways. In particular, we noted low fibrinogen levels and high D-dimer levels with histological liver findings. Our data suggest that fibrinogen and D-dimers may be used as prognostic markers to detect the severity of liver disease in patients with COVID-19. Finally, we underline the crucial role of coagulation balance in subjects with severe forms of COVID-19.