Guide for diagnosis and treatment of hyperphenylalaninemia.

Haruo ShintakuToshihiro OhuraMasaki TakayanagiShigeo KureMisao OwadaYoichi MatsubaraMakoto YoshinoYoshiyuki OkanoTetsuya ItoTorayuki OkuyamaKimitoshi NakamuraMasafumi MatuoFumio EndoHiroyuki Ida

Published in: Pediatrics international : official journal of the Japan Pediatric Society (2021)

If tetrahydrobiopterin-responsive hyperphenylalaninemia is diagnosed, all ages can be treated with sapropterin hydrochloride. Although there are reports that sapropterin hydrochloride is effective and safe for the prevention of maternal phenylketonuria, further investigation is required.

Keyphrases

birth weight
cancer therapy
pregnancy outcomes
adverse drug
drug delivery
body mass index
physical activity
gestational age
weight gain