Robust immunity to influenza vaccination in haematopoietic stem cell transplant recipients following reconstitution of humoral and adaptive immunity.

Wuji ZhangLouise C RowntreeRamona MuttucumaruTimon DamelangMalet AbanAeron C HurtMaria AuladellRobyn EsterbauerBruce WinesMark HogarthStephen J TurnerAdam K WheatleyStephen J KentSushrut PatilSharon AveryOrla MorrisseyAmy W ChungMarios KoutsakosThi H O NguyenAllen C ChengTom C KotsimbosKatherine Kedzierska

Published in: Clinical & translational immunology (2023)

Our study demonstrates efficient, although time-dependent, immune responses to IIV in HSCT recipients, and provides insights into influenza vaccination strategies targeted to immunocompromised high-risk groups.

Keyphrases

immune response
stem cells
dendritic cells
cancer therapy
bone marrow
drug delivery
intensive care unit
inflammatory response
cell therapy