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Bacteriophages as potential antibiotic potentiators in cystic fibrosis: A new model to study the combination of antibiotics with a bacteriophage cocktail targeting dual species biofilms of Staphylococcus aureus and Pseudomonas aeruginosa.

Zhifen WangSteven De SoirAntoine GlorieuxMaya MerabishviliChristiane KnoopDaniel De VosJean-Paul PirnayFrançoise Van Bambeke
Published in: International journal of antimicrobial agents (2024)
Pre-screening inhibition of bacterial respiration by phages may assist in selecting those showing activity at sufficiently low titers to showcase anti-biofilm activity in this complex but clinically-relevant in vitro model of biofilm.
Keyphrases
  • pseudomonas aeruginosa
  • cystic fibrosis
  • staphylococcus aureus
  • biofilm formation
  • candida albicans
  • acinetobacter baumannii
  • lung function
  • cancer therapy
  • escherichia coli
  • risk assessment
  • drug delivery