A comprehensive tractography study of patients with bipolar disorder and their unaffected siblings.

Emma SprootenJennifer BarrettD Reese McKayEmma E KnowlesSamuel R MathiasAnderson M WinklerMargaret S BrumbaughStefanie LandauLindsay CyrPeter KochunovDavid C Glahn

Published in: Human brain mapping (2016)

The differential sensitivity of analysis techniques likely explains between-study heterogeneity in anatomical localization of FA reductions. The present tractography analysis confirms the presence of overall FA reductions in patients with bipolar disorder, which are most pronounced in the superior longitudinal fasciculus. Unaffected siblings may display similar, albeit more subtle and anatomically restricted FA reductions. Hum Brain Mapp 37:3474-3485, 2016. © 2016 Wiley Periodicals, Inc.

Keyphrases

bipolar disorder
major depressive disorder
white matter
intellectual disability
multiple sclerosis
single cell
functional connectivity