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Disclosure of clinically actionable genetic variants to thoracic aortic dissection biobank participants.

Adelyn BeilWhitney HornsbyWendy R UhlmannRajani AatrePatricia ArscottBrooke WolfordKim A EagleBo YangJennifer McNamaraCristen WillerJ Scott Roberts
Published in: BMC medical genomics (2021)
Participants were satisfied with the return of clinically significant biobank genetic results and CLIA laboratory testing; however, the process required significant time and resources. These findings illustrate the trade-offs involved for researchers considering returning research genetic results.
Keyphrases
  • aortic dissection
  • genome wide
  • copy number
  • spinal cord
  • dna methylation
  • gene expression
  • spinal cord injury